HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methacrolein → 2-(3-Fluoro-4-methoxyphenyl)-4-methyl-1-(4-sulfamoylphenyl)pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methacrolein | HCID 6562 | — |
| Reactant | alpha-(3-Fluoro-4-methoxyphenyl)-alpha-(4-sulfamoylanilino)acetonitrile | HCID 21862797 | — |
| Product | 2-(3-Fluoro-4-methoxyphenyl)-4-methyl-1-(4-sulfamoylphenyl)pyrrole | HCID 21862772 | — |
Reaction Steps
Following a procedure similar to that described in Example 1(iii), but using α-(3-fluoro-4-methoxyphenyl)-α-(4-sulfamoylanilino) acetonitrile [prepared as described in step (ii) above] and methacrolein as starting materials, the title compound was obtained as a white powder (yield 28%), melting at 170-173° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05908858 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-f0c048e2e47d4bc8b250b3f13ad2df76 |
| Source note | uspto-grants-1999_06 |