Trimethylsilyl cyanide → HCID 21862869, compound

HRID 1415809Notes

Reaction equation

HRID 1415809 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][C:19]=1[F:20])[CH:5]=[N:6][C:7]1[CH:12]=[CH:11][C:10]([S:13](=[O:16])(=[O:15])[NH2:14])=[CH:9][CH:8]=1.C[Si]([C:25]#[N:26])(C)C>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]([NH:6][C:7]2[CH:12]=[CH:11][C:10]([S:13](=[O:16])(=[O:15])[NH2:14])=[CH:9][CH:8]=2)[C:25]#[N:26])[CH:17]=[CH:18][C:19]=1[F:20]

Participants

3

Reactant 2

HCID 82115Trimethylsilyl cyanideHCID 21862781HCID 21862781, compound

Product 1

HCID 21862869HCID 21862869, compound

Procedure

Following a procedure similar to that described in Example 1(ii), but using N-(3,4-difluorobenzylidene)-4-sulfamoylaniline [prepared as described in step (i) above] and trimethylsilyl cyanide as starting materials, the title compound was obtained as a slightly yellow powder (yield 92%). Nuclear Magnetic Resonance Spectrum (270 MHz, hexadeuterated dimethyl sulfoxide) δ ppm:

Sources & evidence

ORD record
ord-5b2dad7284624b779b075d22c665e65b
Source dataset
uspto-grants-1999_06
Patent number
US05908858

Reaction notes

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