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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1415812Generated: November 2, 2026

Trimethylsilyl cyanide → alpha-(2,4-Difluoroanilino)-alpha-(4-sulfamoylphenyl)acetonitrile

https://huagongshe.com/reaction/1415812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilyl cyanideHCID 82115—
Reactant2,4-Difluoro-N-(4-sulfamoylbenzylidene)anilineHCID 21862783—
Productalpha-(2,4-Difluoroanilino)-alpha-(4-sulfamoylphenyl)acetonitrileHCID 21862810—

Reaction Steps

Following a procedure similar to that described in Example 1(ii), but using 2,4-difluoro-N-(4-sulfamoylbenzylidene)aniline [prepared as described in step (i) above] and trimethylsilyl cyanide as starting materials, the title compound was obtained as a white powder (yield 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05908858
Source datasetuspto-grants-1999_06
ORD IDord-79c74f12e8af4047a120e45302552899
Source noteuspto-grants-1999_06