Methacrolein → 1-(2,4-Difluorophenyl)-4-methyl-2-(4-sulfamoylphenyl)pyrrole

Participants

Reaction Steps

Following a procedure similar to that described in Example 1(iii), but using α-(2,4-difluoroanilino)-α-(4-sulfamoylphenyl)acetonitrile [prepared as described in step (ii) above] and methacrolein as starting materials, the title compound was obtained as a white powder (yield 63%), melting at 140-141° C.

Provenance & Evidence