Methacrolein → 4-Methyl-1-(4-methylthiophenyl)-2-(4-sulfamoylphenyl)pyrrole

HRID 1415831Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1415831
[CH3:1][S:2][C:3]1[CH:22]=[CH:21][C:6]([NH:7][CH:8]([C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:13][CH:12]=2)[C:9]#N)=[CH:5][CH:4]=1.O=[CH:24][C:25](=C)[CH3:26]>>[CH3:26][C:25]1[CH:9]=[C:8]([C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:13][CH:12]=2)[N:7]([C:6]2[CH:21]=[CH:22][C:3]([S:2][CH3:1])=[CH:4][CH:5]=2)[CH:24]=1

Komponenten

3

Edukt 2

HCID 6562MethacroleinHCID 21862767alpha-(4-Methylthioanilino)-alpha-(4-sulfamoylphenyl)acetonitrile

Produkt 1

HCID 99287494-Methyl-1-(4-methylthiophenyl)-2-(4-sulfamoylphenyl)pyrrole

Versuchsvorschrift

Following a procedure similar to that described in Example 1(iii), but using α-(4-methylthioanilino)-α-(4-sulfamoylphenyl)acetonitrile [prepared as described in step (ii) above] and methacrolein as starting materials, the title compound was obtained as a slightly yellow powder (yield 33%), melting at 194-196° C.

Quellen und Nachweise

ORD-Eintrag
ord-4471fcafcac448e6bd83f688c2503141
Quelldatensatz
uspto-grants-1999_06
Patentnummer
US05908858

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