Formaldehyde → HCID 54025620, compound

HRID 1415862Notes

Reaction equation

[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1)([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:8]([O:10][CH2:11][CH3:12])=[O:9].[CH2:25]=O.Cl.[CH3:28][NH:29][CH3:30]>>[CH3:28][N:29]([CH2:25][C:5]1[O:1][C:2]([CH2:6][C:7]([CH2:18][CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:3][CH:4]=1)[CH3:30]

Participants

Reactant 3

HCID 712Formaldehyde

HCID 10473Dimethylamine, hydrochloride

HCID 53690947HCID 53690947, compound

Product 1

HCID 54025620HCID 54025620, compound

Procedure

ethyl 3-(fur-2-yl)-2-cyclohexylmethyl-2-ethoxycarbonyl-propanoate, which by reaction with formaldehyde and dimethylamine hydrochloride yields ethyl 3-(5-dimethylaminomethyl-fur-2-yl)-2-cyclohexylmethyl-2-ethoxycarbonyl-propanoate.

Sources & evidence

ORD record: ord-5f540611a65f43b7bde2e40d06b34d86
Source dataset: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05908863

Reaction notes

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