HRID1415971

反应详情

EQUATION

反应方程式

HRID 1415971 的结构方程式

REACTANTS

反应物

2

结构：CCOC(=O)CC[C@H](NC(=O)c1ccc(NC)cc1)C(=O)OCC

L-Glutamic acid, N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester

C17H24N2O5

结构：Br.Nc1nc(N)c2nc(CBr)cnc2n1

6-(Bromomethyl)-2-imino-2,3-dihydropteridin-4-amine--hydrogen bromide (1/1)

C7H8Br2N6

PRODUCTS

生成物

1

结构：CCOC(=O)CC[C@H](NC(=O)c1ccc(N(C)Cc2cnc3nc(N)nc(N)c3n2)cc1)C(=O)OCC

Diethyl N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamate

C24H30N8O5

PROCEDURE

实验过程

reacting this 6-bromomethyl-2,4-diaminopteridine hydrobromide with diethyl N-[4-(N-methylamino)-benzoyl]glutamate to give diethyl methotrexate, and