HCID 178418361, compound → HCID 178442154, compound

HRID 1416125Notes

Reaction equation

HRID 1416125 reaction equation
C([O:8][CH2:9][C@H:10]1[O:15][CH2:14][C@H:13]([CH:16]2[CH2:21][CH2:20][CH:19]([CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH2:18][CH2:17]2)[CH2:12][O:11]1)C1C=CC=CC=1.[H][H]>C1COCC1.[Pd]>[CH2:22]([CH:19]1[CH2:18][CH2:17][CH:16]([C@@H:13]2[CH2:14][O:15][C@@H:10]([CH2:9][OH:8])[O:11][CH2:12]2)[CH2:21][CH2:20]1)[CH2:23][CH2:24][CH2:25][CH3:26]

Participants

5

Reactant 2

HCID 178418361HCID 178418361, compoundHCID 178442152HCID 178442152, compound

Product 1

HCID 178442154HCID 178442154, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

A solution of 100 mmol of trans/trans-2-benzyloxymethyl-5-(4-pentylcyclohexyl)-1,3-dioxane is hydrogenated in 300 ml of THF with the addition of 2.0 g of 5% Pd/activated charcoal until the take-up of hydrogen is complete. trans/trans-[5-(4-pentylcyclohexyl)-1,3-dioxan-2-yl]methanol is obtained by conventional work-up.

Sources & evidence

ORD record
ord-ff3cb721bd8649839440063b815b25d6
Source dataset
uspto-grants-1999_06
Patent number
US05911912

Reaction notes

Loading…