Ammonium Hydroxide → HCID 17601252, compound

HRID 1416151Notes

Reaction equation

HRID 1416151 reaction equation
[O:1]=[C:2]1[C:11](=[O:12])[NH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([S:13](Cl)(=[O:15])=[O:14])[CH:8]=2)[NH:3]1.[OH-].[NH4+:18]>>[O:1]=[C:2]1[C:11](=[O:12])[NH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([S:13]([NH2:18])(=[O:15])=[O:14])[CH:8]=2)[NH:3]1

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 49837382,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride

Product 1

HCID 17601252HCID 17601252, compoundYield 15%

Procedure

A suspension of 5.21 g (0.02 mole) of 1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinesulfonyl chloride and 40 ml of 25% ammonium hydroxide is stirred at room temperature for 6 hours. Then it is filtered, the separated material is washed with water and acetone, filtered, dried, dissolved in a slight amount of hot dimethyl sulfoxide, and the product is precipitated from the solution by adding a slight amount of 2-propanol to it. Thus 0.70 g (15%) of 1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxaline sulfonamide is obtained, m.p.: >360° C.

Workup

  1. filtrationThen it is filtered
  2. washthe separated material is washed with water and acetone
  3. filtrationfiltered
  4. customdried
  5. dissolutiondissolved in a slight amount of hot dimethyl sulfoxide
  6. customthe product is precipitated from the solution
  7. additionby adding a slight amount of 2-propanol to it

Sources & evidence

ORD record
ord-249b6513d5234f1d86379ba40f4e18a7
Source dataset
uspto-grants-1999_06
Patent number
US05912245

Reaction notes

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