HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → Lamotrigine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 178513162 | HCID 178513162 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Lamotrigine | HCID 3878 | — |
Reaction Steps
(E)-2-(2',3'-dichlorophenyl)-2-(guanidinylimino)acetamide (2.5 g) was dissolved in hot ethanol (40 ml). Potassium hydroxide (2.0 g, equivalent to 5% w/v) was added and the solution was irradiated by exposure to bright sunlight and a tungsten lamp (15W).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05912345 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-c579767fb383410b93f43bcacd771300 |
| Source note | uspto-grants-1999_06 |