HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 67581954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 67581955 | HCID 67581955 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 67581954 | HCID 67581954 | 66.5% |
Reaction Steps
To a suspension of 4-[(2RS,3SR)-(3-hydroxybutan-2-yl)oxy]-2-(1-piperazinyl)quinazoline (cf. Example 46) (600 mg) in acetone (20 ml) is added acetic acid (136 mg), and the mixture is filtered, and the filtrate is allowed to stand at room temperature, and the precipitated crystals are separated by filtration to give 4-[(2RS,3SR)-(3-hydroxybutan-2-yl)oxy]-2-(1-piperazinyl)quinazoline monoacetate (478 mg) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05912247 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-6d7648c7da684b019e22dc87b1fc91b3 |
| Source note | uspto-grants-1999_06 |