Hydrochloride methanol → HCID 67582048, compound

Participants

Reaction Steps

4-[(2R,3R)-(2,3-Dihydroxybutan-1-yl)oxy]-2-(1-piperazinyl)quinazoline (cf. Example 55) (0.85 g) is dissolved in methanol (10 ml), and thereto is added 2N HCl-methanol (1.6 ml), and the mixture is evaporated to dryness under reduced pressure. The resulting residue is recrystallized from ethanol to give 4-[(2R,3R)-(2,3-dihydroxybutan-1-yl)oxy]-2-(1-piperazinyl)quinazoline monohydrochloride (0.3 g).

Provenance & Evidence