HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → 7-[N'-(2-aminoethyl)thioureido]-5-cyano-8-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 5-Cyano-7-isothiocyanato-8-methylquinoline | HCID 18465373 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 7-[N'-(2-aminoethyl)thioureido]-5-cyano-8-methylquinoline | HCID 18465374 | — |
Reaction Steps
A solution of 5-cyano-7-isothiocyanato-8-methylquinoline (0.85 g) in toluene (100 mL) is added dropwise to a solution of ethylenediamine (1.94 g) in toluene (100 mL). A yellow-white precipitate is observed after the reaction stirs at room temperature for 10 minutes. The precipitate is filtered and dried in vacuo to afford 7-[N'-(2-aminoethyl)thioureido]-5-cyano-8-methylquinoline as a yellow-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05916900 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-c3dfa875a4024f4bb3d08b7c9227aa51 |
| Source note | uspto-grants-1999_06 |