反应详情

Using an analogous procedure to that described in Example 2 in the section relating to the preparation of starting materials 3-carboxy-8-nitro-4-oxo-3,4-dihydroquinoline was reacted with thionyl chloride and then concentrated aqueous ammonia. The product so obtained was recrystallised from ethanol to give 3-carbamoyl-4-chloro-8-nitroquinoline in 79% yield, mp 277-279° C.

1. customThe product so obtained
2. customwas recrystallised from ethanol