Taurine → Magnesium taurate

HRID 1417129Notes

Reaction equation

HRID 1417129 reaction equation
[OH-].[Mg+2:2].[OH-].[NH2:4][CH2:5][CH2:6][S:7]([OH:10])(=[O:9])=[O:8]>O.CO>[CH2:5]([NH2:4])[CH2:6][S:7]([O-:10])(=[O:9])=[O:8].[CH2:5]([NH2:4])[CH2:6][S:7]([O-:10])(=[O:9])=[O:8].[Mg+2:2]

Participants

5

Reactant 2

HCID 1123TaurineHCID 73981Magnesium Hydroxide

Product 1

HCID 13343447Magnesium taurate

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

A mixture of magnesium hydroxide (433 mg, 7.46 mmol; Aldrich) and taurine (1.87 g, 14.9 mmol) in 20 ml water was heated under reflux for seven hours. The resulting milky mixture was allowed to cool, diluted with 40 ml methanol and allowed to stand overnight at room temperature. A white powder, consisting mostly of magnesium taurate complex, was removed by filtration. The clear filtrate was concentrated under vacuum to a pasty slurry, then diluted slowly with 10 ml methanol. After 2 hours, crystalline magnesium taurate salt was obtained by filtration. The yield was 940 mg (41%). The melting point (decomposition) was about 300° C. This salt was identical to that obtained in Example 2.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for seven hours
  3. temperatureto cool
  4. customwas removed by filtration
  5. concentrationThe clear filtrate was concentrated under vacuum to a pasty slurry
  6. additiondiluted slowly with 10 ml methanol
  7. waitAfter 2 hours

Sources & evidence

ORD record
ord-07f0f90de0f44fda9e2f4f2117374e0a
Source dataset
uspto-grants-1999_03
Patent number
US05876757

Reaction notes

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