Sodium hydride → HCID 70346516, compound

Participants

Reaction Steps

0.4 g of 7-(4,6-dimethoxypyrimidin-2-yl)-4-(2-thienyl)-7-hydroxyfuro[3,4-b]pyridin-5(7H)one was dissolved in 100 ml of benzene, and 0.05 g of 60% sodium hydride was added thereto under cooling with ice. Then the resulting mixture was stirred at room temperature for one day, and the precipitated crystals were sufficiently washed with benzene to obtain 0.4 g (yield 97%) of the desired compound. m.p.: >300° C.

Provenance & Evidence