Sodium hydride → HCID 70346448, compound

Participants

Reaction Steps

0.4 g of 7-(4,6-dimethoxypyrimidin-2-yl)-4-(4-chlorophenyl)-7-hydroxyfuro[3,4-b]pyridin-5-(7H)one was dissolved in 100 m of toluene, and 0.05 g of 60% sodium hydride was added thereto. The mixture was stirred at room temperature for one day. The precipitated crystals were collected by filtration and sufficiently washed with acetone to obtain 0.25 g (yield 60%) of the desired compound. m.p.: 263°-267° C.

Provenance & Evidence