Sodium chloride; water → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

HRID 1417358Notes

Reaction equation

HRID 1417358 reaction equation
CC(N(C)C)=[O:3].CC1[C@@H](OC([C@H](O)[C@@H](NC(C2C=CC=CC=2)=O)C2C=CC=CC=2)=O)[CH2:24][C@:20]2([OH:47])C(C)(C)C=1[C@@H](OC(C)=O)C([C@@]1(C)[C@H:18]([C@@H:19]2[O:48]C(C2C=CC=CC=2)=O)[C@:17]2([O:59]C(C)=O)[CH2:57][O:58][C@@H]2C[C@@H]1O)=O.[OH2:69].[Na+].[Cl-]>O>[O:69]=[CH:24][C@@H:20]([C@H:19]([C@@H:18]([C@@H:17]([CH2:57][OH:58])[OH:59])[OH:3])[OH:48])[OH:47]

Participants

4

Reactant 2

HCID 57417360Sodium chloride; waterHCID 131721138HCID 131721138, compound

Product 1

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalYield 5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The DMA-paclitaxel mixture was diluted in normal saline or 5% dextrose in water to yield drug concentrations of 1 mg/ml and 5 mg/ml.

Sources & evidence

ORD record
ord-e27b901f8bde45fcb4f8e6343ed0ee72
Source dataset
uspto-grants-1999_03
Patent number
US05877205

Reaction notes

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