反应详情

Combine 8-(t-butoxycarbonyl)amino-octanoic acid methyl-butyl-amide and 4M hydrochloric acid in dioxane (10 mL). After 1 hour, the reaction mixture is evaporated to a residue. Partition the residue between toluene and 1M sodium hydroxide solution. Extract the aqueous layer with toluene. Combine the organic layers, dry over MgSO4, and filter to give the title compound as a toluene solution. Evaporate in vacuo to give the title compound.

1. customthe reaction mixture is evaporated to a residue
2. customPartition the residue between toluene and 1M sodium hydroxide solution
3. extractionExtract the aqueous layer with toluene
4. dry with materialdry over MgSO4
5. filtrationfilter