3-(Benzyloxy)benzyl chloride → tert-Butyl [9-(3-Benzyloxybenzyl)-4-methyl-1-methylthiocarbazol-2-yl]acetate

HRID 1417490Notes

Reaction equation

HRID 1417490 reaction equation
[CH3:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[NH:7][C:6]=2[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=1.[CH2:25]([O:32][C:33]1[CH:34]=[C:35]([CH:38]=[CH:39][CH:40]=1)[CH2:36]Cl)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[CH2:25]([O:32][C:33]1[CH:34]=[C:35]([CH:38]=[CH:39][CH:40]=1)[CH2:36][N:7]1[C:6]2[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=[C:2]([CH3:1])[C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 131734903-(Benzyloxy)benzyl chlorideHCID 54527372Tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate

Product 1

HCID 57238596tert-Butyl [9-(3-Benzyloxybenzyl)-4-methyl-1-methylthiocarbazol-2-yl]acetateYield 78%

Procedure

Following a procedure and using relative proportions of starting materials similar to those described in Example 4, but using tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate and 3-benzyloxybenzyl chloride as starting materials, the title compound was obtained in a yield of 78% as an oil.

Sources & evidence

ORD record
ord-611981a98ec84ab692642e20de7ba35b
Source dataset
uspto-grants-1999_03
Patent number
US05877199

Reaction notes

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