Benzene, 1-(bromomethyl)-3-nitro- → tert-Butyl [4-Methyl-1-methylthio-9-(3-nitrobenzyl)carbazol-2-yl]acetate

HRID 1417491Notes

Reaction equation

HRID 1417491 reaction equation
[CH3:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[NH:7][C:6]=2[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=1.[N+:25]([C:28]1[CH:29]=[C:30]([CH:33]=[CH:34][CH:35]=1)[CH2:31]Br)([O-:27])=[O:26]>>[CH3:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:7]([CH2:31][C:30]3[CH:33]=[CH:34][CH:35]=[C:28]([N+:25]([O-:27])=[O:26])[CH:29]=3)[C:6]=2[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=1

Participants

3

Reactant 2

HCID 77568Benzene, 1-(bromomethyl)-3-nitro-HCID 54527372Tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate

Product 1

HCID 86753776tert-Butyl [4-Methyl-1-methylthio-9-(3-nitrobenzyl)carbazol-2-yl]acetateYield 83%

Procedure

Following a procedure and using relative proportions of starting materials similar to those described in Example 4, but using tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate and 3-nitrobenzyl bromide as starting materials, the title compound was obtained in a yield of 83% as an oil.

Sources & evidence

ORD record
ord-0ec23b5e1adf4f4eac1038c7a94a7f5f
Source dataset
uspto-grants-1999_03
Patent number
US05877199

Reaction notes

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