Glycinamide → 2-[3-(2-Chloro-6-methylphenyl)-thioureido]-acetamide

HRID 1417729Notes

Reaction equation

HRID 1417729 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]=[C:10]=[S:11].[NH2:12][CH2:13][C:14]([NH2:16])=[O:15]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[S:11])[NH:12][CH2:13][C:14]([NH2:16])=[O:15]

Participants

3

Reactant 2

HCID 69020GlycinamideHCID 37317252-Chloro-6-Methylphenyl Isothiocyanate

Product 1

HCID 543940602-[3-(2-Chloro-6-methylphenyl)-thioureido]-acetamide

Procedure

2-[3-(2-Chloro-6-methylphenyl)-thioureido]-acetamide was prepared by the procedure described in Example 2 using 18.3 g of 2-chloro-6-methylphenyl-isothiocyanate and 12.0 g of glycinamide. 22.8 Grams of the product was obtained, m.p. 161°-163° C. (dec.). This compound was used without further purification in the next paragraph.

Workup

  1. custom22.8 Grams of the product was obtained
  2. customThis compound was used without further purification in the next paragraph

Sources & evidence

ORD record
ord-33a23b8281bd47bc8c2a430aa6d5a16e
Source dataset
uspto-grants-1999_03
Patent number
US05877324

Reaction notes

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