反应详情

Using an analogous reaction procedure to that described in Example 6, 6-chloro-4-(3'-chloro-4'-fluoroanilino)pyrimidine was reacted with 3-methoxyaniline. The reaction product was recrystallised from a mixture of methylene chloride, methanol and hexane, to give 4-(3'-chloro-4'-fluoroanilino)-6-(3'-methoxyanilino)pyrimidine in 16% yield, m.p. 214°-216° C.;

1. customan analogous reaction procedure to
2. customThe reaction product was recrystallised from a mixture of methylene chloride, methanol and hexane