3-(4-aminophenoxy)propan-1-ol → HCID 70187799, compound

Participants

Reaction Steps

Using an analogous reaction procedure to that described in Example 6, 4-chloro-6-(3'-methylanilino)pyrimidine (1.35 g) was reacted with 4-(3-hydroxypropoxy)aniline.(1.0 g). The product so obtained was chromatographed on silica and triturated under methylene chloride to give 4-[4'-(3-hydrox-ypropoxy)anilino]6-(3'-methylanilino)pyrimidine in 18% yield, m.p. 196°-200° C.;

Provenance & Evidence