3-Chloro-N,N-dimethyl-1-propanamine → 4-[4'-(3-Dimethylaminopropoxy)anilino]6-(3'-methylanilino)pyrimidine

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Using an analogous reaction procedure to that described in Example 23, 4-(4'-hydroxyanilino)-6-(3'-methylanilino)pyrimidine (0.6 g) was reacted with 3-dimethylaminopropyl chloride. The product so obtained was chromatographed on silica and precipitated from a mixture of methylene chloride, methanol and hexane to give 4-[4'-(3-dimethylaminopropoxy)anilino]6-(3'-methylanilino)pyrimidine in 13% yield, m.p. 204°-207° C.;

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