反应详情

A mixture of 4-[4'-hydroxyanilino]6-(3'-methylanilino)pyrimidine (1.14 g), 1-bromo-2,3-epoxypropane-(0.5 ml) and potassium carbonate (1.24 g) in DMSO (12 ml) was stirred at ambient temperature for 16 hours to give 4-[4'-(2,3-epoxypropoxy)anilino]6-(3'-methylanilino) pyrimidine (0.70 g);