HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → 4-[4'-(2,3-Epoxypropoxy)anilino]6-(3'-methylanilino) pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | Epibromohydrin | HCID 18430 | — |
| Edukt | 4-[4'-Hydroxyanilino]6-(3'-methylanilino)pyrimidine | HCID 54409692 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | 4-[4'-(2,3-Epoxypropoxy)anilino]6-(3'-methylanilino) pyrimidine | HCID 86753853 | — |
Reaktionsschritte
A mixture of 4-[4'-hydroxyanilino]6-(3'-methylanilino)pyrimidine (1.14 g), 1-bromo-2,3-epoxypropane-(0.5 ml) and potassium carbonate (1.24 g) in DMSO (12 ml) was stirred at ambient temperature for 16 hours to give 4-[4'-(2,3-epoxypropoxy)anilino]6-(3'-methylanilino) pyrimidine (0.70 g);
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05880130 |
| Quelldatensatz | uspto-grants-1999_03 |
| ORD ID | ord-2edcbed2e1844b888dfa02244a6fae62 |
| Quellennotiz | uspto-grants-1999_03 |