HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydride → 4-(4-Ethoxyphenyl)-2-fluoro-4-methylpent-2-enol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydride | HCID 62714 | — |
| Reactant | Methyl 2-fluoro-4-(4-ethoxy-phenyl)-4-methylpent-2-enoate | HCID 54191630 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 4-(4-Ethoxyphenyl)-2-fluoro-4-methylpent-2-enol | HCID 53692153 | 90% |
Reaction Steps
The method of Example 6 was repeated using methyl 2-fluoro-4-(4-ethoxy-phenyl)-4-methylpent-2-enoate (Example 4) (0.2 g), diethyl ether (15 ml) and lithium hydride (0.1 g) to yield the title compound (0.16 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05880162 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-447b5bac63ac4362b88372f90bb8017a |
| Source note | uspto-grants-1999_03 |