3-(2,4-Dimethoxy-5-formylphenyl)octanoic acid Methyl 3-(2,4-dimethoxy-5-formylphenyl)octanoate → Methyl 3-(2,4-dimethoxy-5-formylphenyl)octanoate

HRID 1418190Notes

Reaction equation

HRID 1418190 reaction equation
[CH3:1][O:2][C:3](=[O:23])[CH2:4][CH:5]([C:11]1[CH:16]=[C:15]([CH:17]=[O:18])[C:14]([O:19][CH3:20])=[CH:13][C:12]=1[O:21][CH3:22])[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].COC1C=C(OC)C(C=O)=CC=1C(CCCCC)CC(O)=O>C(OCC)(=O)C.CCCCCC>[CH3:22][O:21][C:12]1[CH:13]=[C:14]([O:19][CH3:20])[C:15]([CH:17]=[O:18])=[CH:16][C:11]=1[CH:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH2:4][C:3]([O:2][CH3:1])=[O:23]

Participants

3

Reactant 1

HCID 867538683-(2,4-Dimethoxy-5-formylphenyl)octanoic acid Methyl 3-(2,4-dimethoxy-5-formylphenyl)octanoate

Product 1

HCID 19348477Methyl 3-(2,4-dimethoxy-5-formylphenyl)octanoate

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

32(iii) 3-(2,4-Dimethoxy-5-formylphenyl)octanoic acid Methyl 3-(2,4-dimethoxy-5-formylphenyl)octanoate [prepared as described in step (ii) above] was hydrolyzed in a similar manner to that described in Preparation 7 to give the title compound as crystals, melting at 110°-111.5° C. (from ethyl acetate-hexane).

Workup

  1. customdescribed in Preparation 7

Sources & evidence

ORD record
ord-0d8526252f84461daa23f72dd13c4ca3
Source dataset
uspto-grants-1999_03
Patent number
US05880147

Reaction notes

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