3-Methoxypropyl 4-methylbenzenesulfonate → 3-[4-(3-Methoxypropoxy)-2-methoxyphenyl]heptanoic Acid

Participants

Reaction Steps

Following a similar procedure to that described in Preparation 45A(i), but using methyl 3-(4-hydroxy-2-methoxyphenyl)heptanoate (prepared as described in Preparation 58A), and 3-methoxy-1-tosyloxypropane, the corresponding ether derivative was obtained. Hydrolysis of this derivative and subsequent treatment of the reaction mixture were conducted in a similar manner to that described in Preparation 7 to give the title compound as an oily substance.

Provenance & Evidence