Dimethylamine, hydrochloride → 2-t-Butyl-5-(N,N-dimethylcarbamoyl)-1-nitrobenzene

HRID 1418232Notes

Reaction equation

HRID 1418232 reaction equation
[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9](O)=[O:10])=[CH:7][C:6]=1[N+:14]([O-:16])=[O:15])([CH3:4])([CH3:3])[CH3:2].Cl.[CH3:18][NH:19][CH3:20]>>[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9](=[O:10])[N:19]([CH3:20])[CH3:18])=[CH:7][C:6]=1[N+:14]([O-:16])=[O:15])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 10473Dimethylamine, hydrochlorideHCID 7388134-Tert-butyl-3-nitrobenzoic acid

Product 1

HCID 193486712-t-Butyl-5-(N,N-dimethylcarbamoyl)-1-nitrobenzene

Procedure

Following a similar procedure to that described in Preparation 4, but using 4-t-butyl-3-nitrobenzoic acid and dimethylamine hydrochloride instead of methanol, the title compound was obtained as an oily substance.

Workup

  1. customthat described in Preparation 4

Sources & evidence

ORD record
ord-571da359513b4e959e12956ea428c7d8
Source dataset
uspto-grants-1999_03
Patent number
US05880147

Reaction notes

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