2-Bromoethyl methyl ether → Methyl 3-[2-methoxy-4-(2-methoxyethoxy)phenyl]-5-methylhexanoate

HRID 1418236Notes

Reaction equation

HRID 1418236 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH2:14][CH:15]([CH3:17])[CH3:16])[CH2:9][C:10]([O:12][CH3:13])=[O:11])=[C:4]([O:18][CH3:19])[CH:3]=1.[CH3:20][O:21][CH2:22][CH2:23]Br>>[CH3:19][O:18][C:4]1[CH:3]=[C:2]([O:1][CH2:23][CH2:22][O:21][CH3:20])[CH:7]=[CH:6][C:5]=1[CH:8]([CH2:14][CH:15]([CH3:17])[CH3:16])[CH2:9][C:10]([O:12][CH3:13])=[O:11]

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 19348568Methyl 3-(4-hydroxy-2-methoxyphenyl)-5-methylhexanoate

Product 1

HCID 19348474Methyl 3-[2-methoxy-4-(2-methoxyethoxy)phenyl]-5-methylhexanoate

Procedure

Following a similar procedure to that described in Preparation 45A(i), but using methyl 3-(4-hydroxy-2-methoxyphenyl)-5-methylhexanoate (prepared as described in Preparation 58B) and 2-methoxyethyl bromide, the title compound was obtained as an oily substance.

Workup

  1. customthat described in Preparation 45A(i)

Sources & evidence

ORD record
ord-1f438e339b3c4fc09acc0914e3b795a8
Source dataset
uspto-grants-1999_03
Patent number
US05880147

Reaction notes

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