Cesium carbonate → HCID 9848132, compound

Participants

Reaction Steps

3.3 g of caesium carbonate are added to a solution of 1.55 g of 2,3-dihydro-4,6-dimethylpyridazin-3-one (prepared according to F. H. McMillan et al., J. Am.Chem. Soc. 78, 407 (1956)) and 4.52 g of 2-(1,3-benzodioxol-5-yl)-2-bromo-N-(4-isopropylphenylsulfonyl)acetamide in 100 ml of DMF. The mixture is stirred at room temperature for 2 hours and worked up in the customary manner and 2-(1,3-benzodioxol-5-yl)-2-(2,3-dihydro-4,6-dimethylpyridazin-3-on-2-yl)N-(4-isopropylphenylsulfonyl)acetamide is obtained, m.p. 105°.

Provenance & Evidence