Sodium Hydroxide → HCID 15379787, compound

HRID 1418323Notes

Reaction equation

HRID 1418323 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([N:15]3[C:20](=[O:21])[C:19]([CH3:22])=[CH:18][C:17]([CH3:23])=[N:16]3)[C:11]([O:13]C)=[O:12])=[CH:9][C:4]=2[O:3][CH2:2]1.[OH-].[Na+]>CO>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([N:15]3[C:20](=[O:21])[C:19]([CH3:22])=[CH:18][C:17]([CH3:23])=[N:16]3)[C:11]([OH:13])=[O:12])=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 15379786HCID 15379786, compound

Product 1

HCID 15379787HCID 15379787, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 2.24 g of methyl 2-(1,3-benzodioxol-5-yl)-2-(4,6-dimethyl-2,3-dihydropyridazin-3-on-2-yl)-acetate in 20 ml of methanol is treated with 7.08 ml of 1N sodium hydroxide solution and the mixture is stirred at room temperature for 18 hours. It is worked up in the customary manner and 2-(1,3-benzodioxol-5-yl)-2-(4,6-dimethyl-2,3-dihydropyridazin-3-on-2-yl)acetic acid is obtained, m.p. 165°, EI 302.

Sources & evidence

ORD record
ord-e2f1b64f92704763ac3a43e63be4113d
Source dataset
uspto-grants-1999_03
Patent number
US05883090

Reaction notes

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