Sodium Hydroxide → HCID 15379787, compound

Participants

Reaction Steps

A solution of 2.24 g of methyl 2-(1,3-benzodioxol-5-yl)-2-(4,6-dimethyl-2,3-dihydropyridazin-3-on-2-yl)-acetate in 20 ml of methanol is treated with 7.08 ml of 1N sodium hydroxide solution and the mixture is stirred at room temperature for 18 hours. It is worked up in the customary manner and 2-(1,3-benzodioxol-5-yl)-2-(4,6-dimethyl-2,3-dihydropyridazin-3-on-2-yl)acetic acid is obtained, m.p. 165°, EI 302.

Provenance & Evidence