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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1418353Generated: November 4, 2026

4-Isopropylaniline → N-(4-isopropylphenyl)-3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionamide

https://huagongshe.com/reaction/1418353

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-IsopropylanilineHCID 7464—
Reactant3-[6-(4-t-Butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionic acidHCID 15381103—
ProductN-(4-isopropylphenyl)-3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionamideHCID 17764550—

Reaction Steps

The procedure described in Example 2 was repeated by use of 3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy )-2-morpholino-4-pyrimidinyloxy]propionic acid and 4-isopropylaniline, to thereby obtain the title compound as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05883092
Source datasetuspto-grants-1999_03
ORD IDord-ac25223c58674755bdc26797e75aa201
Source noteuspto-grants-1999_03