HRID1418353

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7464

Cumidine

C9H13N

反应SMILES：COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(N2CCOCC2)nc1OCCC(=O)O

HCID15381103

未命名化合物

PRODUCTS

产物

反应SMILES：COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(N2CCOCC2)nc1OCCC(=O)Nc1ccc(C(C)C)cc1

HCID17764550

未命名化合物

PROCEDURE

实验过程

The procedure described in Example 2 was repeated by use of 3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy )-2-morpholino-4-pyrimidinyloxy]propionic acid and 4-isopropylaniline, to thereby obtain the title compound as a colorless oil.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-ac25223c58674755bdc26797e75aa201
来源数据集: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US05883092
来源说明: uspto-grants-1999_03

反应SMILES

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)[N:18]=[C:17]([O:27][CH2:28][CH2:29][C:30]([OH:32])=O)[C:16]=2[O:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=2[O:40][CH3:41])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH:42]([C:45]1[CH:51]=[CH:50][C:48]([NH2:49])=[CH:47][CH:46]=1)([CH3:44])[CH3:43]>>[CH:42]([C:45]1[CH:51]=[CH:50][C:48]([NH:49][C:30](=[O:32])[CH2:29][CH2:28][O:27][C:17]2[C:16]([O:33][C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=3[O:40][CH3:41])=[C:15]([NH:14][S:11]([C:8]3[CH:9]=[CH:10][C:5]([C:1]([CH3:2])([CH3:4])[CH3:3])=[CH:6][CH:7]=3)(=[O:13])=[O:12])[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)[N:18]=2)=[CH:47][CH:46]=1)([CH3:44])[CH3:43]