Diethyl Ether → HCID 57247189, compound

Participants

Reaction Conditions

Reaction Steps

Ethyl isocyanate (0.85 ml, 0.76 g, 10.7 mmol) was added dropwise with stirring to 4-piperidone ethylene ketal (1.43 g, 10 mmol) in dry dichloromethane (30 ml). The resulting pale yellow solution was stirred at 20° C. for 24 h, then evaporated to yield a yellow solid. Trituration with ether gave the title compound as a white crystalline solid (1.85 g), m.p. 120°-122° C.

Provenance & Evidence