Ethyl 4-oxo-1-piperidinecarboxylate → HCID 67568422, compound

HRID 1418384Notes

Reaction equation

HRID 1418384 reaction equation
Cl.Cl.[Cl:3][C:4]1[CH:12]=[CH:11][CH:10]=[C:9]([NH2:13])[C:5]=1[C:6]([NH2:8])=[NH:7].O=[C:15]1[CH2:20][CH2:19][N:18]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH2:17][CH2:16]1>>[ClH:3].[NH2:7][C:6]1[C:5]2[C:9](=[CH:10][CH:11]=[CH:12][C:4]=2[Cl:3])[NH:13][C:15]2([CH2:20][CH2:19][N:18]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH2:17][CH2:16]2)[N:8]=1

Participants

3

Reactant 2

HCID 34767Ethyl 4-oxo-1-piperidinecarboxylateHCID 67568344HCID 67568344, compound

Product 1

HCID 67568422HCID 67568422, compound

Procedure

This was prepared by the method of Example 173 using 2-chloro-6-anino benzamidine dihydrochloride (Example B) and ethyl 4-oxopiperidine-1-carboxylate giving the title compound, m.p. 181°-183° C.

Sources & evidence

ORD record
ord-351adb75b88042b88cbec4259bcbc139
Source dataset
uspto-grants-1999_03
Patent number
US05883102

Reaction notes

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