Ethyl 4-oxo-1-piperidinecarboxylate → HCID 9950613, compound

HRID 1418389Notes

Reaction equation

HRID 1418389 reaction equation
[ClH:1].Cl.[F:3][C:4]1[CH:12]=[CH:11][CH:10]=[C:9]([NH:13][CH3:14])[C:5]=1[C:6]([NH2:8])=[NH:7].O=[C:16]1[CH2:21][CH2:20][N:19]([C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH2:18][CH2:17]1>>[ClH:1].[NH2:8][C:6]1[C:5]2[C:9](=[CH:10][CH:11]=[CH:12][C:4]=2[F:3])[N:13]([CH3:14])[C:16]2([CH2:21][CH2:20][N:19]([C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH2:18][CH2:17]2)[N:7]=1

Participants

3

Reactant 2

HCID 34767Ethyl 4-oxo-1-piperidinecarboxylateHCID 67568350HCID 67568350, compound

Product 1

HCID 9950613HCID 9950613, compound

Procedure

This was prepared by the method of Example 173 using 2-fluoro-6-(methylamino)benzamidine dihydrochloride (Example K) and ethyl 4-oxopiperidine-1-carboxylate to give the title compound, m.p. 234°-235° C.

Sources & evidence

ORD record
ord-8d068d6f792b489493ed11aac8f59943
Source dataset
uspto-grants-1999_03
Patent number
US05883102

Reaction notes

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