HCID 21192811, compound → HCID 21192802, compound

Participants

Reaction Steps

Phenylmethyl 4'-Amino-5'-fluorospiro[azetidine-3 ,2'(1'H)-quinazoline]-1 -carboxylate (Example 249, 1 g, 2.94 mmol) in ethanol (50 ml) containing 10% palladium on carbon catalyst (0.1 g) was stirred under hydrogen at 3 atmospheres pressure for 48 h. The catalyst was removed by filtration and the filtrate concentrated to leave the crude title compound as a gum (0.6 g), MS (+CI) 207 ([M+H]+).

Provenance & Evidence