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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1418449Generated: November 1, 2026

CJ-13454 → 1-[5-Fluoro-3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxamide

https://huagongshe.com/reaction/1418449

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCJ-13454HCID 9931329—
ReactantEthyl 1-[3-fluoro-5-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxylateHCID 18786351—
Product1-[5-Fluoro-3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxamideHCID 9800723—

Reaction Steps

The desired compound was prepared from ethyl 1-[3-fluoro-5-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxylate according to the preparation of 4-[5-fluoro-3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6- tetrahydro-2H-pyran-4-carboxamide (Example 5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05883106
Source datasetuspto-grants-1999_03
ORD IDord-1717b8aa0924448b8b1544e17dcb2522
Source noteuspto-grants-1999_03