Acetate → (1,1'-Biphenyl)-4-carbonitrile

HRID 141846Notes

Reaction equation

HRID 141846 reaction equation
[CH2:21]1[O:22][CH2:23][CH2:24][O:25][CH2:26]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[NH2:19][PH2:20].[O-:28][C:29]([CH3:30])=[O:31].[O-:32][C:33]([CH3:34])=[O:35].[OH:10][B:11]([OH:12])[c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1.[Pd+2:27]>>[c:2]1(-[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 121634-ChlorobenzonitrileHCID 312751,4-DioxaneHCID 66827Phenylboronic AcidHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 15520603Aminophosphine

Product 1

HCID 18021(1,1'-Biphenyl)-4-carbonitrile

Sources & evidence

ORD record
ord-1ca7c257ca63461b8bbed07d007951ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…