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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1418487Generated: October 31, 2026

HCID 11380253, compound → HCID 11166621, compound

https://huagongshe.com/reaction/1418487

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11380253HCID 11380253—
Reactant4-(2-Methylimidazol-1-yl)benzyl chloride hydrochlorideHCID 18786342—
ProductHCID 11166621HCID 1116662149%

Reaction Steps

Methyl 4-(2,5-difluoro-3-hydroxyphenyl)-3,4,5,6-tetrahydropyran-4-carboxylate was reacted with 4-(2-methylimidazol-1-yl)benzyl chloride hydrochloride according to the procedure described in Example 2H to give the titled compound in 49% yield as a yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05883106
Source datasetuspto-grants-1999_03
ORD IDord-9e92fcac297d4e818b5fd74f93d3b54e
Source noteuspto-grants-1999_03