Trifluoroacetic acid → HCID 53661008, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure in Example 3B except using (±)-8-methyl-7-[1-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-1-oxopropyl]oxy]propyl]indolizino[1,2-b]quinolin-9(11H)-one. 1H NMR (DMSO-d6) d 8.67 (s, 1H), 8.11 (m, 2H), 7.84 (m, 1H), 7.70 (m, 1H), 7.21 (s, 1H), 5.85 (dd, J=7.9, 5.8 Hz, 1H), 5.25 (s, 2H), 2.24 (s, 3H), 2.1-1.83 (m, 2H), 1.52 (s, 3H), 1.49 (s, 3H), 0.97 (t, J=7.3 Hz, 3H). Anal. Calcd for C23H25N3O3.CF3CO2H.2 H2O: C, 55.45; H, 5.58; N, 7.76. Found: C, 55.85; H, 5.19; N, 7.83.

Provenance & Evidence