Pyridine → HCID 86753927, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure in Example 13 except using (±)-7-[1-[(iodoacetyl)oxy]propyl]-8-methylindolizino[1,2-b]quinolin-9(11H)-one and pyridine. 1H NMR (CDCl3 /MeOH-d4) d 9.09 (d, J=5.5 Hz, 2H), 8.65 (t, J=7.9 Hz, 1H), 8.51 (s, 1H), 8.17 (m, 3H), 7.99 (d, J=8.1 Hz, 1H). 7.89 (m, 1H), 7.70 (m, 1H), 7.50 (s, 1H), 6.05 (d, J=17.2 Hz, 1H), 6.02 (m, 1H).5.87 (d, J=17.2 Hz, 1H), 5.30 (s, 2H), 2.31 (s, 3H), 2.18-1.94 (m, 2H), 1.09 (t, J=7.4 Hz, 3H). Anal. Calcd for C26H24IN3O3.1/4 H2O: C, 55.97; H, 4.43; N, 7.53. Found: C, 55.72; H, 4.30; N, 7.26.

Provenance & Evidence