1-(4-Fluorophenyl)piperazine → HCID 9883823, compound

HRID 1418885Notes

Reaction equation

HRID 1418885 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1.C[C:15]1[CH:16]=[C:17]([N:22]2CC[NH:25][CH2:24][CH2:23]2)[CH:18]=[CH:19][C:20]=1[CH3:21]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH2:13][CH2:12][N:11]([CH2:21][C:20]3[CH:19]=[C:18]4[C:17](=[CH:16][CH:15]=3)[NH:22][CH2:23][CH2:24][NH:25]4)[CH2:10][CH2:9]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 752601-(4-Fluorophenyl)piperazineHCID 27237821-(3,4-Xylyl)piperazine

Product 1

HCID 9883823HCID 9883823, compound

Procedure

Example 6 was prepared according to Example 2 except that in Step A 1-(4-fluorophenyl)piperazine is substituted for 1-(3,4-dimethylphenyl)piperazine; mp 126°-127° C.

Workup

  1. customExample 6 was prepared

Sources & evidence

ORD record
ord-ccfa56eeab984e7d827236a8bac8ff4f
Source dataset
uspto-grants-1999_03
Patent number
US05885994

Reaction notes

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