Hydrochloric Acid → HCID 86753979, compound

Participants

Reaction Steps

A suspension of 0.12 g of 5-[4-(5-hydroxy-1,4,6,7-tetramethylbenzimidazol-2-ylmethoxy)benzyl]thiazolidine-2,4-dione (prepared as described in Example 3) in 3 ml of a 4N solution of hydrogen chloride in ethyl acetate was stirred for 3 hours at room temperature, after which it was allowed to stand overnight. Insoluble substances were collected by filtration and washed with tetrahydrofuran, with ethyl acetate and with diethyl ether, in that order, to give 0.11 g of the title compound, melting at 228°-231° C.

Provenance & Evidence