HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → HCID 178516780, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 4-aminoacetyl-1-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-5-(dimethylaminomethyleneamino)imidazole | HCID 53794522 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178516780 | HCID 178516780 | — |
Reaction Steps
In step 18, compound (24) is dissolved in methanol and treated with a methanolic solution of sodium methylate at room temperature to effect the ring-formation of the substituents on the imidazole ring of compound (24). Thus, 3-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-6,7-dihydroimidazo-[4,5-d] [1,3]diazepin-8(3H)-one [compound (25)] is produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05886167 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-d6e5e195ec6d4d1cae489c8c5d4439a3 |
| Source note | uspto-grants-1999_03 |