HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid methylene chloride → N-Methyl-N-[2-(piperidin-4-yl)phenyl]methanesulfonamide Trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Reactant | N-[2-(1-t-Butoxycarbonylpiperidin-4-yl)phenyl]-N-methylmethanesulfonamide | HCID 67553893 | — |
| Product | N-Methyl-N-[2-(piperidin-4-yl)phenyl]methanesulfonamide Trifluoroacetate | HCID 86753991 | — |
Reaction Steps
N-[2-(1-t-Butoxycarbonylpiperidin-4-yl)phenyl]-N-methylmethanesulfonamide (662 mg) was dissolved in trifluoroacetic acid-dichloromethane (10%, 50 mL) and stirred at room temperature 2 h. The solvent was evaporated under reduced pressure to give the title compound as a colourless gum (670 mg), m/e (ES+) 269 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05885999 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-c75b51c4a6dd40fd82419d66578e5a77 |
| Source note | uspto-grants-1999_03 |